NJ Bio Inc., Princeton
New Jersey, United States
NJ Bio Inc., Princeton
New Jersey, United StatesThe NJ Bio, Inc., Princeton facility houses multiple specialized laboratories, including those for bioconjugation, linker–payload and high-potency API (HPAPI) synthesis, protein and antibody production, functional assays, process development, and analytical method development. It also includes suites for GMP manufacturing with accompanying analytical labs. The site is equipped with advanced instrumentation and state-of-the-art laboratories, to support development of complex modalities of all types such as bioconjugates. The facility’s integrated resources ensure seamless support across the entire drug development process, accelerating programs from discovery to the clinic.
NJ Bio Inc., Princeton
New Jersey, United States
Capabilities
- Bioconjugation: R&D and GMP manufacturing (Phase I & II)
- Antibody-drug conjugates (ADCs): R&D to GMP manufacturing (Phase I & II)
- Antibody- Oligonucleotide Conjugates (AOCs): R&D to GMP manufacturing (Phase I & II)
- Linker-Payloads & Small molecules: Synthesis from R&D to GMP manufacturing (Phase I & II)
- Oligonucleotides & Analogs: Custom synthesis and purification of oligonucleotides, NTPs, nucleosides & capping analogs
- mRNA synthesis
- Targeted protein degraders
- Radiopharmaceuticals: Ligand synthesis and conjugates
- Characterization & Testing: Analytical, bioanalytical, bioassay and NMR (Center of Excellence)
Production Capacity
Research & Development
- Bioconjugation (R&D): mg to 500g
- Linker-payload synthesis: 10mg to 200g
- Synthesis & purification of customized Oligonucleotides, NTPs, Nucleosides & Capping analogs: 10mg to 60g
- Small molecules (General API & HPAPI): mg to kg scale
- mRNA scalability: 1µg (Small scale) to 20g (Large scale)
- Antibody Production: 50mL to 4L
- Payload-Linker Development: Scale-up to 50 - 500g (Process / High Potent Suite)
- Bioconjugation Development: Scale-up to 2 - 50L (Purification / TFF Capabilities)
- Bioconjugation & Biologics Manufacturing: Up to 50L Reactor size
- Chemical Technologies Manufacturing - HPAPI/Cytotoxic: 200 – 500g; API: 500 – 1000g
- cGMP and non-GMP small molecule/payload-linker manufacturing (scale: 50 – 500g)
- Small scale (2 – 50L) suite to manufacture mRNA, antibody conjugates, and other biopharmaceutical products to support Tox and Phase I
Equipment & Utilities
Mass spectrometry:
- QTof system
- UPLC w/ Tof MS detectors
- SQDs
- HPLC with UV detector
- HPLC with autosampler and fraction collector
- UPLC systems
- Combiflash EZ Prep flash/ HPLC purification system
- Combiflash Rf flash systems
- FPLC & SFC systems
- Other chromatography systems
- 800-MHz NMR spectrometer with cryoprobe
- 700-MHz NMR spectrometer with cryoprobe
- 300 – 500MHz NMR spectrometers with multinuclear probes
- Bioreactors
- TFF systems
- Flow cytometer
- Live-cell analysis system
- Automated cell counting system
- Automated liquid handling system
- Multiplexing plate reader
- Biolayer interferometry system
- Bacterial Endotoxin testing system
- Oligonucleotide synthesizer
- Automated peptide synthesizer
- Imager
- Microwave reactor
- Photoreactor with 450W UV Lamp
- Inert atmosphere glovebox
- Negative pressure isolators
- 5L Jacketed reactor with temperature control system
- Lyophilizers
- Multiple fume hoods
- HPLC/ UPLC
- GC
- MS
- cIEF
- Differential scanning calorimeter
- TOC analyzer
- Capillary electrophoresis systems
- Microplate readers
- HVAC
- Purified water systems
- Compressed gas
- Vacuum system
- Electrical power & backups
- Waste handling systems
Capabilities
Multi-scale cGMP intermediate & API manufacturing
Production Capacity
Total Reactor Volume: 406 KL
Annual Output Capacity: XXX MT
Block-wise Capacity:
| Block | Capacity | Key Features |
|---|---|---|
| Block A | 60 KL | Intermediate Manufacturing |
| Block B | 166 KL | API Manufacturing |
| Block C | 110 KL | High-Potency Handling |
| Block D | 10.5 KL | Pilot Scale Production |
Equipment & Utilities
Reactor Types
- Glass-lined
- Stainless Steel
Reactor Range
From [XX L] to [YY KL]
Key Equipment
- Centrifuges
- Dryers (ANFDs, Tray Dryers, RCVDs)
- Distillation Units
- Micronizers
Utilities Infrastructure
- HVAC Systems
- Boilers with backup power
- Chillers and Cooling Towers
- Purified Water and WFI Systems
- Nitrogen Generation Plant
- Reactor Types: Glass-lined, Stainless Steel
- Reactor Range: From [XX L] to [YY KL]
- Key Equipment:
- Centrifuges
- Dryers (ANFDs, Tray Dryers, RCVDs)
- Distillation Units
- Micronizers
- Utilities Infrastructure:
- HVAC Systems
- Boilers with backup power
- Chillers and Cooling Towers
- Purified Water and WFI Systems
- Nitrogen Generation Plant
Accreditation
History
Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet
Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet
Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet
Lorem ipsum
Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet
Experience
Our great team of more than 1400 software experts.
Quick Support
We’ll help you test bold new ideas while sharing your.
Leadership Team
John Smith
CEO
Emma London
Co-Founder
Jessica Brown
Managing Director
Christine Eve
Designer
Sustainability
ESG
Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet
EHS
Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet
Quality & Compliance
Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet
We deal With The Aspects Of Professional IT Services
About usEngitech is the partner of choice for many of the world’s leading enterprises, SMEs and technology challengers. We help businesses elevate their value through custom software development, product design,
Experience
Our great team of more than 1400 software experts.
Quick Support
We’ll help you test bold new ideas while sharing your.
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna.
440
employees from around the world
+
640
happy clients from largest corporations
+
0
offices in 6 counties worldwide
We deal With The Aspects Of Professional IT Services
About usEngitech is the partner of choice for many of the world’s leading enterprises, SMEs and technology challengers. We help businesses elevate their value through custom software development, product design,
UI/UX Design
95%
App Development
82%
Business Growth
90%
Technology Solution
80%
Science & Technology
Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet Lorem ipsum dolor sit amet
John Smith
A leading Company
Here’s What’s Happening
From our blog
