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Powering Your Pipeline with Science and Speed
Overview
At Cohance Lifesciences, we bring scientific rigor and operational agility to the development of small molecule APIs, advanced intermediates and starting materials. Our end-to-end capabilities span route scouting, process optimization, analytical development, and regulatory documentation—empowering innovators to move confidently from concept to clinic.
With deep expertise across hazardous, moisture-sensitive, and stereoselective chemistries, our dedicated process R&D teams engineer robust, scalable, and cost-effective synthesis pathways. Every step is underpinned by integrated process safety, data integrity, and global compliance, ensuring a smooth transition to GMP manufacturing and regulatory submissions.
Why Cohance for Small Molecule Development?
Why Cohance for Small Molecule Development?
- 100+ scientists dedicated to small molecule R&D
- Experience in 20+ reaction classes (e.g., hydrogenation, cyanation, cryogenics)
- Flow chemistry excellence: PFRs, photo flow, CSTRs
- Integrated safety studies and scalability assessment
- Fully equipped R&D facility at Genome Valley, Hyderabad
Featured Services
Route
Scouting
Efficient identification of optimal synthetic routes using DoE and feasibility studies.
Process Development
& Optimization
Risk-informed development, impurity profiling, and scalable optimization for cost and purity.
Analytical
Development
Custom methods, impurity markers, validation, and stability-indicating assays.
Process Safety
& Risk Evaluation
State-of-the-art safety studies (RC1, DSC, ARC) to ensure secure scale-up.
Regulatory
Documentation
Comprehensive support for IND, IMPD, and DMF submissions across global markets.
Route
Scouting
Efficient identification of optimal synthetic routes using DoE and feasibility studies.
Process Development
& Optimization
Risk-informed development, impurity profiling, and scalable optimization for cost and purity.
Analytical
Development
Custom methods, impurity markers, validation, and stability-indicating assays.
Process Safety
& Risk Evaluation
State-of-the-art safety studies (RC1, DSC, ARC) to ensure secure scale-up.
Regulatory
Documentation
Comprehensive support for IND, IMPD, and DMF submissions across global markets.
Integrated Development Services
Early Phase Development
Lab-scale feasibility, synthetic optimization, and impurity identification.
Scale-Up Readiness
Execution of engineering and validation batches using advanced reactors and process tools.
Lifecycle Services
Rework/reprocessing studies, solvent recovery, impurity fate, and purge investigations.
Special Capabilities
Expertise in hazardous reactions, air-/moisture-sensitive chemistries, stereoselective synthesis, and more.
Contact Us