Sapala Organics, IDA Mallapur

Telangana, India

Sapala Organics, IDA Mallapur

Telangana, India

Sapala Organics is a pioneering force in nucleic acid innovation in India. With over a century of combined expertise across 18 laboratories, the company specializes in modified nucleosides, advanced building blocks, and custom phosphoramidites that enable breakthrough therapies. Following its acquisition by Cohance Lifesciences, Sapala now integrates three decades of Cohance’s CDMO excellence, reinforcing its role as a trusted global partner in nucleic acid chemistry and oligonucleotide-based therapeutics.

Key offerings: Nucleic acid chemistry and oligonucleotide-based therapeutics

Sapala Organics, IDA Mallapur

Telangana, India

Research & Development

Contract Research Services under CRO model with Full-Time Equivalent (FTE) scientists
Embedded scientific teams for collaborative, long-term partnerships
Tailored R&D programs ensuring deep alignment with client objectives

Process Development

Scale-up of modified phosphoramidites and nucleoside triphosphates
Process development of oligonucleotides using modified phosphoramidites
Process optimisation of various of drug delivery compounds such as GalNAc
Development of custom linkers, spacers and fluorescent dyes

Manufacturing

CDMO services in nucleic acid chemistry for global clients
Integrated expertise in oligonucleotide-based therapeutics
Part of Cohance Lifesciences network, ensuring world-class standards

Sapala Organics, IDA Mallapur (Telangana, India)

Equipment & Utilities

Spectroscopy & NMR: FTIR (2), NMR (400 MHz, 500 MHz)
Chromatography: HPLC (9 systems: UV, RI, ELSD, CAD), GC, GC-HS, UPLC
Spectrometry: UPLC(2), LC-MS (2), GC-MS, LC-MS/MS, ICP-MS
Spectrophotometry: UV, Polarimeter, Optical rotation, Specific optical rotation
Thermal Studies: DSC, TGA, Melting/Boiling point analysis
Wet Analysis: Autotitrator, Gravimetric, Argentometric, Heavy metal analysis, ROI, KF Coulometer, Conductivity, KF Titrator
Oligonucleotide Equipment: Akta Oligosynth; Akta Oligopilot-10 and NTS-24 column synthesiser

Capabilities

Multi-scale cGMP intermediate & API manufacturing

Production Capacity

Total Reactor Volume: 406 KL

Annual Output Capacity: XXX MT

Block-wise Capacity:

Block	Capacity	Key Features
Block A	60 KL	Intermediate Manufacturing
Block B	166 KL	API Manufacturing
Block C	110 KL	High-Potency Handling
Block D	10.5 KL	Pilot Scale Production

Total Number of Reactors: 89

Equipment & Utilities

Reactor Types

Glass-lined
Stainless Steel

Reactor Range

From [XX L] to [YY KL]

Key Equipment

Centrifuges
Dryers (ANFDs, Tray Dryers, RCVDs)
Distillation Units
Micronizers

Utilities Infrastructure

HVAC Systems
Boilers with backup power
Chillers and Cooling Towers
Purified Water and WFI Systems
Nitrogen Generation Plant

Reactor Types: Glass-lined, Stainless Steel
Reactor Range: From [XX L] to [YY KL]
Key Equipment:
- Centrifuges
- Dryers (ANFDs, Tray Dryers, RCVDs)
- Distillation Units
- Micronizers

Utilities Infrastructure:
- HVAC Systems
- Boilers with backup power
- Chillers and Cooling Towers
- Purified Water and WFI Systems
- Nitrogen Generation Plant

Accreditation

History

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Experience

Our great team of more than 1400 software experts.

Quick Support

We’ll help you test bold new ideas while sharing your.

Leadership Team

John Smith

CEO

Emma London

Co-Founder

Jessica Brown

Managing Director

Christine Eve

Designer

Sustainability

ESG

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EHS

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Quality & Compliance

We deal With The Aspects Of Professional IT Services

About us

Engitech is the partner of choice for many of the world’s leading enterprises, SMEs and technology challengers. We help businesses elevate their value through custom software development, product design,

Experience

Our great team of more than 1400 software experts.

Quick Support

We’ll help you test bold new ideas while sharing your.

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440

employees from around the world

+ 640

happy clients from largest corporations

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offices in 6 counties worldwide

We deal With The Aspects Of Professional IT Services

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UI/UX Design

95%

App Development

82%

Business Growth

90%

Technology Solution

80%

Science & Technology

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Sapala Organics, IDA Mallapur

Sapala Organics, IDA Mallapur

Sapala Organics, IDA Mallapur

Sapala Organics, IDA Mallapur

Capabilities

Production Capacity

Research & Development

Process Development

Manufacturing

Equipment & Utilities

Accreditations & Certifications

Capabilities

Production Capacity

Equipment & Utilities

Accreditation

History

Lorem ipsum

Experience

Quick Support

Leadership Team

Sustainability

ESG

EHS

Quality & Compliance

We deal With The Aspects Of Professional IT Services

Experience

Quick Support

We deal With The Aspects Of Professional IT Services

Science & Technology

Here’s What’s Happening

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